FANCJ/BRIP1 is an iron-sulfur (FeS) cluster-binding DNA helicase involved in DNA inter-strand cross-link (ICL) repair and G-quadruplex (G4) metabolism. Mutations in FANCJ are associated with Fanconi anemia and an increased risk for developing breast and ovarian cancer. Several cancer-associated mutations are located in the FeS domain of FANCJ. but how they affect FeS cluster binding a... https://www.roneverhart.com/MSI-Vector-GP68HX-12VH-012CA-16-FHD-Gaming-Laptop-Intel-Core-i9-12900HX-2-30-GHz-32GB-DDR5-1TB-SSD-GeForce-RTX-4080-W/